Mammalian sperm cell

Sperm , also called spermatozoon, plural spermatozoa , male reproductive cell , produced by most animals. With the exception of nematode worms, decapods e. In higher vertebrates, especially mammals, sperm are produced in the testes. The sperm unites with fertilizes an ovum egg of the female to produce a new offspring. Mature sperm have two distinguishable parts, a head and a tail.

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Update on mammalian sperm capacitation: how much does the horse differ from other species?

Dynamics of the mammalian sperm plasma membrane in the process of fertilization. - Semantic Scholar

Mammalian sperm cells undergo a process called capacitation, which readies them for fertilization. Transmembrane adenylyl cyclases tmACs have been speculated to be involved. Furthermore, the investigators showed that cAMP signaling pathways are compartmentalized in the sperm cell. A pathway with heterotrimeric G s proteins and tmAC functions in the head; another pathway with the soluble adenylyl cyclase Adcy10 and protein kinase A is responsible for cAMP signaling in the flagellum and controls sperm motility. Proposed model for the spatial distribution of cAMP in sperm functions. You'll be in good company.
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Thermotaxis of mammalian sperm cells: A potential navigation mechanism in the female genital tract

Published as paper no. The investigations reported in this paper are part of a comprehensive study on the physiology of spermatozoa which is being conducted by the Animal Breeding Section of the Division of Animal and Poultry Husbandry of the University of Minnesota under the direction of Dr. Laurence M. Use the link below to share a full-text version of this article with your friends and colleagues. Learn more.
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A major puzzle in biology is how mammalian sperm maintain the correct swimming direction during various phases of the sexual reproduction process. Whilst chemotaxis may dominate near the ovum, it is unclear which cues guide spermatozoa on their long journey towards the egg. Hypothesized mechanisms range from peristaltic pumping to temperature sensing and response to fluid flow variations rheotaxis , but little is known quantitatively about them. We report the first quantitative study of mammalian sperm rheotaxis, using microfluidic devices to investigate systematically swimming of human and bull sperm over a range of physiologically relevant shear rates and viscosities. Our measurements show that the interplay of fluid shear, steric surface-interactions, and chirality of the flagellar beat leads to stable upstream spiralling motion of sperm cells, thus providing a generic and robust rectification mechanism to support mammalian fertilisation.
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