X-linked intellectual disability previously known as X-linked mental retardation refers to forms of intellectual disability which are specifically associated with X-linked recessive inheritance. As with most X-linked disorders, males are more heavily affected than females. Unlike many other types of intellectual disability, the genetics of these conditions are relatively well understood. Several X-linked syndromes include intellectual disability as part of the presentation. These include:. Following is a list of genes located on the X chromosome and linked to intellectual disability.
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Submitted by a public library in Illinois, this one is pretty obvious. It uses old terminology, for starters. Wikipedia has a good article that explains the history of terminology for what we now refer to as intellectual disability. In other words, library books on special needs have to be kept up to date so that they reflect the current terminology at the very least. There are also advances in therapies, treatments, and learning strategies that need to be kept up to date, plus the further definition of conditions that fall under intellectual disability. Downs Syndrome? To some extent, this reflects the changing focus of the group, originally children, then intellectually-disabled people in general, and, finally, the transition from institutionalized care to living more independently in the greater community.
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Change in Terminology: “Mental Retardation” to “Intellectual Disability”
Study record managers: refer to the Data Element Definitions if submitting registration or results information. Abnormal repetitive behaviors odd or inappropriate movements, self-injury, and compulsions are among the aberrant behaviors exhibited by individuals with mental retardation. However, little is known about their pathobiology and treatments are largely unconfirmed by controlled trials. For example, few controlled studies have examined the efficacy of pharmacological treatment of abnormal repetitive behavior in individuals with mental retardation. This trial is part of a larger project designed to elucidate the neurobiological bases of repetitive behavior disorders and to develop rational, safe, and effective pharmacological treatments.
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